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1996-02-27
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Document 0305
DOCN M9630305
TI [Eosinophilic pustular folliculitis and Ofuji disease. A case report]
DT 9603
AU Rotoli M; Carlesimo F; Cavalieri S; Clinica Dermatologica, Universita
Cattolica del Sacro Cuore,; Roma.
SO Recenti Prog Med. 1995 Oct;86(10):386-90. Unique Identifier : AIDSLINE
MED/96094185
AB We describe the case of a young man of Calabrian origin, who came to our
observation for the appearance of erythematous pustular, intensely
itching, lesions on the arms, trunk and, in a less extent, on the face.
The blood count revealed a differential cell count of 16.8% eosinophils.
Serum IgE levels were elevated (1000 IU/ml), and T cell subsets showed
an increase in CD8+ and a decrease in CD4+ with an inversion of
CD4+/CD8+ ratio (= 0.78). The result of the following investigations
were either normal or negative: anti-(ds)DNA antibody, anti-nuclear
antibody, anti-smooth muscle antibody, anti-striated muscle antibody,
serological tests for viral, bacterial, fungal and parasitic diseases
and cultural examination of the material from lesion. Histopathological
examination of a biopsy specimen from the left arm showed the presence
of abundant perivascular inflammatory infiltrate in the dermis and
inflammatory infiltrate, with numerous eosinophils, around sebaceous
glands. Taken together, all these data suggest the diagnosis of
eosinophilic pustular folliculitis, a dermatosis of unknown etiology,
with a histopathological picture identical to Ofuji's disease.
Eosinophilic pustular folliculitis can be associated with HIV infection
or haematological diseases (as non-Hodgkin lymphomas, myeloma, etc.); it
was also reported in adult immunocompetent healthy individuals and in
children. On the basis of our findings, we propose that this case should
be classified as an idiopathic form, as we were not able to demonstrate
any associated disease.
DE Adult Anti-Inflammatory Agents, Steroidal/THERAPEUTIC USE Case Report
English Abstract *Eosinophils *Folliculitis/DRUG THERAPY/PATHOLOGY
Follow-Up Studies Human Infant, Newborn Male Middle Age
Prednisone/ADMINISTRATION & DOSAGE/THERAPEUTIC USE Syndrome Time
Factors JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).